Complement Activation Predicts Adverse Pregnancy Outcome in Patients with Systemic Lupus Erythematosus and/or Anti-Phospholipid Antibodies

OBJECTIVE: Studies in mouse models implicate complement activation as a causative factor in adverse pregnancy outcomes (APOs). We investigated whether activation of complement early in pregnancy predicts APOs in women with systemic lupus erythematosus (SLE) and/or antiphospholipid antibodies (aPL)....

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Kim, Mimi Y., Guerra, Marta M., Kaplowitz, Elianna, Laskin, Carl A., Petri, Michelle, Branch, D. Ware, Lockshin, Michael D., Sammaritano, Lisa R., Merrill, Joan T., Porter, T. Flint, Sawitzke, Allen, Lynch, Anne, Buyon, Jill P., Salmon, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037302/
https://ncbi.nlm.nih.gov/pubmed/29371202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2017-212224
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