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Highly diastereoselective synthesis of modified nucleosides via an asymmetric multicomponent reaction()
We have developed a practical synthesis of unique nucleoside derivatives via TiCl(4) promoted multicomponent reaction of optically active dihydrofuran, ethyl pyruvate/glyoxylate, and a TMS protected nucleobase in a single-pot operation.
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| Publicado no: | Chem Commun (Camb) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037177/ https://ncbi.nlm.nih.gov/pubmed/20449255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b924807b |
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