Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link

Catalpol, an iridoid glucoside, has been found present in large quantities in the root of Rehmannia glutinosa L. and showed a strong antioxidant capacity in the previous study. In the present work, the protective effect of catalpol against AS via inhibiting oxidative stress, DNA damage, and telomere...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhang, Yukun, Wang, Changyuan, Jin, Yue, Yang, Qining, Meng, Qiang, Liu, Qi, Dai, Yongguo, Cai, Lifei, Liu, Zhihao, Liu, Kexin, Sun, Huijun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036816/
https://ncbi.nlm.nih.gov/pubmed/30046372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2876350
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