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WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics

The characteristic of carcinoma is cell migration and invasion, which involve in strong actin dynamics. Regulations of actin dynamics have been implicated in cancer cell migration and tumor progression. WDR1 (WD-repeat domain 1) is a major cofactor of the actin depolymerizing factor (ADF)/cofilin, s...

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Detalles Bibliográficos
Publicado en:Int J Biol Sci
Main Authors: Yuan, Baiyin, Zhang, Ruirui, Hu, Jisheng, Liu, Zhongying, Yang, Chao, Zhang, Tongcun, Zhang, Chenxi
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036740/
https://ncbi.nlm.nih.gov/pubmed/29989053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.23845
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