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How Tumor Cells Choose Between Epithelial-Mesenchymal Transition and Autophagy to Resist Stress—Therapeutic Implications

Tumor cells undergo epithelial-mesenchymal transition (EMT) or macroautophagy (hereafter autophagy) in response to stressors from the microenvironment. EMT ensues when stressors act on tumor cells in the presence of nutrient sufficiency, and mechanistic target of rapamycin (mTOR) appears to be the c...

詳細記述

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書誌詳細
出版年:Front Pharmacol
主要な著者: Marcucci, Fabrizio, Rumio, Cristiano
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036460/
https://ncbi.nlm.nih.gov/pubmed/30013478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00714
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