Stereotactic image-based histological analysis reveals a correlation between (11)C-methionine uptake and MGMT promoter methylation in non-enhancing gliomas

Gliomas are genetically and histopathologically heterogeneous. Intratumoral heterogeneity in the MGMT promoter methylation status is an important clinical biomarker of glioblastoma. A higher uptake of (11)C-methionine in positron-emission tomography (PET) reportedly reflects increased MGMT promoter...

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Publicado en:Oncol Lett
Main Authors: Okita, Yoshiko, Shofuda, Tomoko, Kanematsu, Daisuke, Yoshioka, Ema, Kodama, Yoshinori, Mano, Masayuki, Kinoshita, Manabu, Nonaka, Masahiro, Nakajima, Shin, Fujinaka, Toshiyuki, Kanemura, Yonehiro
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2018
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036429/
https://ncbi.nlm.nih.gov/pubmed/30008885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8866
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