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Vγ9Vδ2 T Cells in the Bone Marrow of Myeloma Patients: A Paradigm of Microenvironment-Induced Immune Suppression

Vγ9Vδ2 T cells are non-conventional T cells with a natural inclination to recognize and kill cancer cells. Malignant B cells, including myeloma cells, are privileged targets of Vγ9Vδ2 T cells in vitro. However, this inclination is often lost in vivo due to multiple mechanisms mediated by tumor cells...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Castella, Barbara, Foglietta, Myriam, Riganti, Chiara, Massaia, Massimo
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036291/
https://ncbi.nlm.nih.gov/pubmed/30013559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01492
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