Effects of Tranexamic Acid Based on its Population Pharmacokinetics in Pediatric Patients Undergoing Distraction Osteogenesis for Craniosynostosis: Rotational Thromboelastometry (ROTEM(TM)) Analysis

Background: Distraction osteogenesis for craniosynostosis is associated with significant hemorrhage. Additionally, patients usually require several transfusions. Tranexamic acid (TXA) is effective for reducing blood loss and the need for transfusions during surgeries. However, the significance of TX...

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Veröffentlicht in:Int J Med Sci
Hauptverfasser: Kim, Eun Jung, Kim, Yong Oock, Shim, Kyu Won, Ko, Byung Woong, Lee, Jong Wha, Koo, Bon-Nyeo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2018
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Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036088/
https://ncbi.nlm.nih.gov/pubmed/30008588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.25008
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