Toxicity and Safety Evaluation of Doxorubicin-Loaded Cockleshell-Derived Calcium Carbonate Nanoparticle in Dogs

Doxorubicin (DOX) is a potent anticancer agent with cytotoxic effects which limit its clinical usage. This effect is due to its nonselective nature causing injury to the cells as a result of reactive free oxygen radical's release. Cockleshell-derived calcium carbonate nanoparticle (CS-CaCO(3)NP...

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Bibliographische Detailangaben
Veröffentlicht in:Adv Pharmacol Sci
Hauptverfasser: Danmaigoro, Abubakar, Selvarajah, Gayathri Thevi, Mohd Noor, Mohd Hezmee, Mahmud, Rozi, Abu Bakar, Md Zuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035816/
https://ncbi.nlm.nih.gov/pubmed/30079088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4848602
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