Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis

Heat shock factor 1 (HSF1) generally exhibits its properties under stress conditions. In tumors, HSF1 has a pleiotropic feature in regulating growth, survival, and aggressiveness of cancer cells. In this study, we found HSF1 was increased in colorectal cancer (CRC) and had a positive correlation wit...

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Publicat a:Mol Ther
Autors principals: Li, Jiaqiu, Song, Ping, Jiang, Tingting, Dai, Dongjun, Wang, Hanying, Sun, Jie, Zhu, Liyuan, Xu, Wenxia, Feng, Lifeng, Shin, Vivian Y., Morrison, Helen, Wang, Xian, Jin, Hongchuan
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035735/
https://ncbi.nlm.nih.gov/pubmed/29730197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.014
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