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MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma

BACKGROUND: Multiple myeloma (MM) patients with t(14;20) have a poor prognosis and their outcome has not improved following the introduction of bortezomib (Bzb). The mechanism underlying the resistance to proteasome inhibitors (PIs) for this subset of patients is unknown. METHODS: IC50 of Bzb and ca...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Qiang, Ya-Wei, Ye, Shiqiao, Huang, Yuhua, Chen, Yu, Van Rhee, Frits, Epstein, Joshua, Walker, Brian A., Morgan, Gareth J., Davies, Faith E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035431/
https://ncbi.nlm.nih.gov/pubmed/29980194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4602-4
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