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Unlocking pandemic potential: prevalence and spatial patterns of key substitutions in avian influenza H5N1 in Egyptian isolates

BACKGROUND: Avian influenza H5N1 has a high human case fatality rate, but is not yet well-adapted to human hosts. Amino acid substitutions currently circulating in avian populations may enhance viral fitness in, and thus viral adaptation to, human hosts. Substitutions which could increase the risk o...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Young, Sean G., Kitchen, Andrew, Kayali, Ghazi, Carrel, Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035396/
https://ncbi.nlm.nih.gov/pubmed/29980172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-018-3222-6
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