Multiple liver insults synergize to accelerate experimental hepatocellular carcinoma

The urgent unmet need for hepatocellular carcinoma (HCC) therapies is addressed here by characterising a novel mouse model of HCC in the context of ongoing liver damage and overnutrition. Male C57Bl/6J mice were treated with diethylnitrosamine (DEN) and thioacetamide (TAA), and some were provided wi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Henderson, James M., Polak, Natasa, Chen, Jinbiao, Roediger, Ben, Weninger, Wolfgang, Kench, James G., McCaughan, Geoffrey W., Zhang, Hui Emma, Gorrell, Mark D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035229/
https://ncbi.nlm.nih.gov/pubmed/29980757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28486-8
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