Iron-Overload triggers ADAM-17 mediated inflammation in Severe Alcoholic Hepatitis

Severe alcoholic hepatitis (SAH) is associated with iron accumulation in hepatocytes/macrophages. This possibly correlates with inflammation and stress but the exact mechanism still remains obscure. To understand the role of iron and the mechanisms of systemic iron-overload, a transcriptomic study o...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Maras, Jaswinder Singh, Das, Sukanta, Sharma, Sachin, Sukriti, Sukriti, kumar, Jitendra, Vyas, Ashish Kumar, Kumar, Dhananjay, Bhat, Adil, Yadav, Gaurav, Choudhary, Manish Chandra, Sharma, Shvetank, kumar, Guresh, Bihari, Chhagan, Trehanpati, Nirupma, Maiwall, Rakhi, Sarin, Shiv Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035223/
https://ncbi.nlm.nih.gov/pubmed/29980709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28483-x
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