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Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes

Trypanosoma brucei, the agents of African trypanosomiasis, undergo density-dependent differentiation in the mammalian bloodstream to prepare for transmission by tsetse flies. This involves the generation of cell-cycle arrested, quiescent, stumpy forms from proliferative slender forms. The signalling...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: McDonald, Lindsay, Cayla, Mathieu, Ivens, Alasdair, Mony, Binny M., MacGregor, Paula, Silvester, Eleanor, McWilliam, Kirsty, Matthews, Keith R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034907/
https://ncbi.nlm.nih.gov/pubmed/29940034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007145
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