Health-related quality of life, neuropsychiatric symptoms and structural brain changes in clinically isolated syndrome

BACKGROUND: Neuropsychiatric symptoms and reduced health-related quality of life (HRQoL) are frequent in multiple sclerosis, where are associated with structural brain changes, but have been less studied in clinically isolated syndrome (CIS). OBJECTIVE: To characterize HRQoL, neuropsychiatric sympto...

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Vydáno v:PLoS One
Hlavní autoři: Hyncicova, Eva, Kalina, Adam, Vyhnalek, Martin, Nikolai, Tomas, Martinkovic, Lukas, Lisy, Jiri, Hort, Jakub, Meluzinova, Eva, Laczó, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034869/
https://ncbi.nlm.nih.gov/pubmed/29979757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200254
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