Scavenging Reactive Oxygen Species Production Normalizes Ferroportin Expression and Ameliorates Cellular and Systemic Iron Disbalances in Hemolytic Mouse Model

Aims: Release of large amounts of free heme into circulation, overproduction of reactive oxygen species (ROS), and activation of toll-like receptor-4-dependent responses are considered critical for the ability of heme to promote oxidative stress and to initiate proinflammatory responses, posing a se...

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Publicat a:Antioxid Redox Signal
Autors principals: Tangudu, Naveen Kumar, Alan, Betül, Vinchi, Francesca, Wörle, Katharina, Lai, Dilay, Vettorazzi, Sabine, Leopold, Kerstin, Vujić Spasić, Maja
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2018
Matèries:
Original Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034398/
https://ncbi.nlm.nih.gov/pubmed/29212341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2017.7089
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