The impact of common genetic variants in the mitochondrial glycine cleavage system on relevant metabolites

The glycine cleavage system (GCS) is a complex of four enzymes enabling glycine to serve as a source of one-carbon units to the cell. We asked whether concentrations of glycine, dimethylglycine, formate, and serine in blood are influenced by variation within GCS genes in a sample of young, healthy i...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab Rep
Main Authors: O'Reilly, Jessica, Pangilinan, Faith, Hokamp, Karsten, Ueland, Per M., Brosnan, John T., Brosnan, Margaret E., Brody, Lawrence C., Molloy, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034155/
https://ncbi.nlm.nih.gov/pubmed/29988937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2018.05.006
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