Effect of a cathepsin K inhibitor on arthritis and bone mineral density in ovariectomized rats with collagen-induced arthritis

OBJECTIVES: Cathepsin K is expressed by osteoclasts and synovial fibroblasts and degrades key components of bone and cartilage. Inhibition of cathepsin K protease activity may be beneficial for the prevention of bone erosion and cartilage degradation in rheumatoid arthritis (RA). The collagen-induce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Bone Rep
Main Authors: Yamashita, Takahiro, Hagino, Hiroshi, Hayashi, Ikuta, Hayashibara, Masako, Tanida, Atsushi, Nagira, Keita, Fukui, Ryohei, Nagashima, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034140/
https://ncbi.nlm.nih.gov/pubmed/29992179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2018.05.006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados