Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid

Women of reproductive age with a Lactobacillus-dominated vaginal microbiota have a reduced risk of acquiring and transmitting HIV and a vaginal pH of ~4 due to the presence of ~1% (wt/vol) lactic acid. While lactic acid has potent HIV virucidal activity in vitro, whether lactic acid present in the v...

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Veröffentlicht in:mSphere
Hauptverfasser: Tyssen, David, Wang, Ying-Ying, Hayward, Joshua A., Agius, Paul A., DeLong, Kevin, Aldunate, Muriel, Ravel, Jacques, Moench, Thomas R., Cone, Richard A., Tachedjian, Gilda
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034077/
https://ncbi.nlm.nih.gov/pubmed/29976641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00055-18
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