The incretin hormone GIP is upregulated in patients with atherosclerosis and stabilizes plaques in ApoE(−/−) mice by blocking monocyte/macrophage activation

OBJECTIVE: The incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic peptide) are secreted by the gut after food intake leading to pancreatic insulin secretion and glucose lowering. Beyond its role in glucose control, GLP-1 was found in mice and men to beneficia...

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Publicado en:Mol Metab
Autores principales: Kahles, Florian, Liberman, Ana, Halim, Constantin, Rau, Matthias, Möllmann, Julia, Mertens, Robert Werner, Rückbeil, Marcia, Diepolder, Irmgard, Walla, Benedikt, Diebold, Sebastian, Burgmaier, Mathias, Lebherz, Corinna, Marx, Nikolaus, Lehrke, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034034/
https://ncbi.nlm.nih.gov/pubmed/29884547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.05.014
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