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In Vitro Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4(+) T Cells Harboring Reactivated Human Immunodeficiency Virus

In the attempt of purging the HIV-1 reservoir through the “shock-and-kill” strategy, it is important to select latency-reversing agents (LRAs) devoid of deleterious effects on the antiviral function of immune effector cells. Here, we investigated two LRAs with PKC agonist activity, prostratin (PRO)...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Desimio, Maria Giovanna, Giuliani, Erica, Ferraro, Angelo Salvatore, Adorno, Gaspare, Doria, Margherita
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033996/
https://ncbi.nlm.nih.gov/pubmed/30008723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01514
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