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Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro

The importance of natural IgM antibodies in protection against infections is still emerging and these antibodies have a potential role in the maintenance of homeostasis through clearance of apoptotic bodies, complement-dependent mechanisms, inflammation and exclusion of misfolded proteins. Natural I...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Devito, Claudia, Ellegård, Rada, Falkeborn, Tina, Svensson, Lennart, Ohlin, Mats, Larsson, Marie, Broliden, Kristina, Hinkula, Jorma
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033918/
https://ncbi.nlm.nih.gov/pubmed/29977063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28242-y
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