Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27

Free fatty acids (FFAs), which are elevated with metabolic syndrome, are considered the principal offender exerting lipotoxicity. Few previous studies have reported a causal relationship between FFAs and osteoarthritis pathogenesis. However, the molecular mechanism by which FFAs exert lipotoxicity a...

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Detalhes bibliográficos
Publicado no:Bone Res
Main Authors: Lee, Sung Won, Rho, Jee Hyun, Lee, Sang Yeob, Chung, Won Tae, Oh, Yoo Jin, Kim, Jung Ha, Yoo, Seung Hee, Kwon, Woo Young, Bae, Ju Yong, Seo, Su Young, Sun, Hokeun, Kim, Hye Young, Yoo, Young Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033867/
https://ncbi.nlm.nih.gov/pubmed/30002945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-018-0020-0
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