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Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders

Glutamate is the predominant excitatory neurotransmitter in the human brain and it has been shown that prolonged activation of the glutamatergic system leads to nerve damage and cell death. Following release from the pre-synaptic neuron and synaptic transmission, glutamate is either taken up into th...

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Veröffentlicht in:World J Psychiatry
Hauptverfasser: Parkin, Georgia M, Udawela, Madhara, Gibbons, Andrew, Dean, Brian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Inc 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033743/
https://ncbi.nlm.nih.gov/pubmed/29988908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5498/wjp.v8.i2.51
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