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Prenatal detection of thalassemia by cell-free fetal DNA (cffDNA) in maternal plasma using surface enhanced Raman spectroscopy combined with PCR

Thalassemias are widely occurring genetic hemoglobin disorders; patients with severe thalassemia often require regular blood transfusions for survival. Prenatal detection of thalassemia is currently invasive and carries the risk of miscarriage and infection. A polymerase chain reaction (PCR)-based s...

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Detalhes bibliográficos
Publicado no:Biomed Opt Express
Main Authors: Li, Xiaozhou, Yang, Tianyue, Li, Caesar Siqi, Jin, Lili, Lou, Hong, Song, Youtao
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033558/
https://ncbi.nlm.nih.gov/pubmed/29984090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.9.003167
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