Human T(SCM) cell dynamics in vivo are compatible with long-lived immunological memory and stemness

Adaptive immunity relies on the generation and maintenance of memory T cells to provide protection against repeated antigen exposure. It has been hypothesised that a self-renewing population of T cells, named stem cell–like memory T (T(SCM)) cells, are responsible for maintaining memory. However, it...

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Udgivet i:PLoS Biol
Main Authors: Costa del Amo, Pedro, Lahoz-Beneytez, Julio, Boelen, Lies, Ahmed, Raya, Miners, Kelly L., Zhang, Yan, Roger, Laureline, Jones, Rhiannon E., Marraco, Silvia A. Fuertes, Speiser, Daniel E., Baird, Duncan M., Price, David A., Ladell, Kristin, Macallan, Derek, Asquith, Becca
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033534/
https://ncbi.nlm.nih.gov/pubmed/29933397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005523
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