CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes

BACKGROUND: In mammalian females, progressive activation of dormant primordial follicles in adulthood is crucial for the maintenance of the reproductive lifespan. Misregulated activation of primordial follicles leads to various ovarian diseases, such as premature ovarian insufficiency (POI). Althoug...

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Bibliographic Details
Published in:BMC Biol
Main Authors: Yan, Hao, Zhang, Jiawei, Wen, Jia, Wang, Yibo, Niu, Wanbao, Teng, Zhen, Zhao, Tongtong, Dai, Yanli, Zhang, Yan, Wang, Chao, Qin, Yingying, Xia, Guoliang, Zhang, Hua
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033292/
https://ncbi.nlm.nih.gov/pubmed/29976179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0541-4
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