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Polycyclic Indoline‐Benzodiazepines through Electrophilic Additions of α‐Imino Carbenes to Tröger Bases

Polycyclic indoline‐benzodiazepines can be accessed through the intermolecular reaction of Tröger bases with N‐sulfonyl‐1,2,3‐triazoles. Under Rh(II) catalysis, α‐imino carbenes are generated and a subsequent cascade of [1,2]‐Stevens, Friedel–Crafts, Grob, and aminal formation reactions yield the po...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Bosmani, Alessandro, Guarnieri‐Ibáñez, Alejandro, Goudedranche, Sébastien, Besnard, Céline, Lacour, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033154/
https://ncbi.nlm.nih.gov/pubmed/29673027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201803756
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