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Mitochondrial dysfunction suppresses p53 expression via calcium-mediated nuclear factor-kB signaling in HCT116 human colorectal carcinoma cells

Mitochondrial DNA (mtDNA) mutations are often observed in various cancer types. Although the correlation between mitochondrial dysfunction and cancer malignancy has been demonstrated by several studies, further research is required to elucidate the molecular mechanisms underlying accelerated tumor d...

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Publicado en:BMB Rep
Autores principales: Lee, Young-Kyoung, Yi, Eui-Yeun, Park, Shi-Young, Jang, Won-Jun, Han, Yu-Seon, Jegal, Myeong-Eun, Kim, Yung-Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033070/
https://ncbi.nlm.nih.gov/pubmed/29580374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2018.51.6.232
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