Heterozygosity for the alpha‐1‐antitrypsin Z allele in cirrhosis is associated with more advanced disease

Alpha‐1‐antitrypsin deficiency (A1ATD) due to homozygosity for the Z allele (ZZ) is an established risk factor for cirrhosis, but the liver disease risk in heterozygous Z allele carriers (MZ) is controversial. The aim of the present study was to determine the prevalence of the MZ genotype among pati...

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Detalhes bibliográficos
Publicado no:Liver Transpl
Main Authors: Schaefer, Benedikt, Mandorfer, Mattias, Viveiros, André, Finkenstedt, Armin, Ferenci, Peter, Schneeberger, Stefan, Tilg, Herbert, Zoller, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032913/
https://ncbi.nlm.nih.gov/pubmed/29573137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.25057
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