Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice

BACKGROUND: Diabetes is a proinflammatory state. Fibrosis of the renal glomerulus is the most common cause of end-stage renal disease. Glomerulosclerosis is caused by the accumulation of extracellular matrix (ECM) proteins in the mesangial interstitial space. Mesangial cells are unique stromal cells...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Principais autores: Hsieh, Ching-Chuan, Lin, Chun-Liang, He, Jie-Teng, Chiang, Meihua, Wang, Yuhsiu, Tsai, Yu-Chin, Hung, Chien-Hui, Chang, Pey-Jium
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032782/
https://ncbi.nlm.nih.gov/pubmed/29973247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0915-0
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