ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma

AT-rich interactive domain 1A (ARID1A) and AT-rich interactive domain 1B (ARID1B) are subunits of the SWI/SNF chromatin complex. ARID1A is a tumor suppressor gene that is frequently mutated (46%) in ovarian clear cell carcinomas (OCCC). Loss of ARID1B in an ARID1A-deficient background eliminates the...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Sato, Emi, Nakayama, Kentaro, Razia, Sultana, Nakamura, Kohei, Ishikawa, Masako, Minamoto, Toshiko, Ishibashi, Tomoka, Yamashita, Hitomi, Iida, Kouji, Kyo, Satoru
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032401/
https://ncbi.nlm.nih.gov/pubmed/29890703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061710
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