Ru(II)-Thymine Complex Causes Cell Growth Inhibition and Induction of Caspase-Mediated Apoptosis in Human Promyelocytic Leukemia HL-60 Cells

Ruthenium-based compounds represent a class of potential antineoplastic drugs. Recently, we designed, synthesized, and identified the Ru(II)-thymine complex [Ru(PPh(3))(2)(Thy)(bipy)]PF(6) (where PPh = triphenylphosphine, Thy = thymine and bipy = 2,2′-bipyridine) as a potent cytotoxic agent with the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: de Souza Oliveira, Maiara, de Santana, Ádila Angélica Dantas, Correa, Rodrigo S., Soares, Milena Botelho Pereira, Batista, Alzir Azevedo, Bezerra, Daniel Pereira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032384/
https://ncbi.nlm.nih.gov/pubmed/29848969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061609
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