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G protein-coupled receptor kinase-2-deficient mice are protected from dextran sodium sulfate-induced acute colitis

G protein-coupled receptor kinase 2 (GRK2) is a serine/threonine kinase and plays a key role in different disease processes. Previously, we showed that GRK2 knockdown enhances wound healing in colonic epithelial cells. Therefore, we hypothesized that ablation of GRK2 would protect mice from dextran...

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Détails bibliographiques
Publié dans:Physiol Genomics
Auteurs principaux: Steury, Michael D., Kang, Ho Jun, Lee, Taehyung, Lucas, Peter C., McCabe, Laura R., Parameswaran, Narayanan
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032290/
https://ncbi.nlm.nih.gov/pubmed/29570431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00006.2018
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