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Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development

Transcription factors are proteins able to bind DNA and induce the transcription of specific genes. Consequently, they play a pivotal role in multiple cellular pathways and are frequently over-expressed or dysregulated in cancer. Here, we will focus on a specific “signal transducer and activator of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sgrignani, Jacopo, Garofalo, Maura, Matkovic, Milos, Merulla, Jessica, Catapano, Carlo V., Cavalli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032208/
https://ncbi.nlm.nih.gov/pubmed/29843450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061591
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