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Sex and nitric oxide bioavailability interact to modulate interstitial Po(2) in healthy rat skeletal muscle

Premenopausal women express reduced blood pressure and risk of cardiovascular disease relative to age-matched men. This purportedly relates to elevated estrogen levels increasing nitric oxide synthase (NOS) activity and NO-mediated vasorelaxation. We tested the hypotheses that female rat skeletal mu...

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Bibliographic Details
Published in:J Appl Physiol (1985)
Main Authors: Craig, Jesse C., Colburn, Trenton D., Hirai, Daniel M., Schettler, Michael J., Musch, Timothy I., Poole, David C.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032088/
https://ncbi.nlm.nih.gov/pubmed/29369738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01022.2017
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