Dominant-Negative DISC1 Alters the Dopaminergic Modulation of Inhibitory Interneurons in the Mouse Prefrontal Cortex

A truncated disrupted in schizophrenia 1 (Disc1) gene increases the risk of psychiatric disorders, probably affecting cortical interneurons. Here, we sought to determine whether this cell population is affected in mice carrying a truncated (Disc1) allele (DN-DISC1). We utilized whole cell recordings...

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Publicat a:Mol Neuropsychiatry
Autors principals: Cardarelli, Ross A., Martin, Rolicia, Jaaro-Peled, Hanna, Sawa, Akira, Powell, Elizabeth M., O'Donnell, Patricio
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2018
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032035/
https://ncbi.nlm.nih.gov/pubmed/29998115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000488030
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