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Mechanical challenges and cytoskeletal impairments in focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) is a histologically defined form of kidney injury typically mediated by podocyte dysfunction. Podocytes rely on their intricate actin-based cytoskeleton to maintain the glomerular filtration barrier in the face of mechanical challenges resulting from pulsati...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Feng, Di, DuMontier, Clark, Pollak, Martin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031906/
https://ncbi.nlm.nih.gov/pubmed/29363327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00641.2017
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