PEP06 polypeptide 30 exerts antitumour effect in colorectal carcinoma via inhibiting epithelial–mesenchymal transition

BACKGROUND AND PURPOSE: PEP06, a polypeptide modified from endostatin, was investigated for its antitumour effects on colorectal cancer (CRC) and the possible mechanisms of this antitumour activity were examined in in vitro and in vivo models. EXPERIMENTAL APPROACH: After PEP06 treatment, cell proli...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Yu, Siming, Li, Linna, Tian, Wei, Nie, Dan, Mu, Wei, Qiu, Fang, Liu, Yu, Liu, Xinghan, Wang, Xiaofeng, Du, Zhimin, Chu, Wen‐Feng, Yang, Baofeng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031886/
https://ncbi.nlm.nih.gov/pubmed/29722931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14352
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