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QM Cluster or QM/MM in Computational Enzymology: The Test Case of LigW-Decarboxylase

The catalytic mechanism of the decarboxylation of 5-carboxyvanillate by LigW producing vanillic acid has been studied by using QM cluster and hybrid QM/MM methodologies. In the QM cluster model, the environment of a small QM model is treated with a bulky potential while two QM/MM models studies incl...

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Publicado en:Front Chem
Autores principales: Prejanò, Mario, Marino, Tiziana, Russo, Nino
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031855/
https://ncbi.nlm.nih.gov/pubmed/30003076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00249
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