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Biomarkers for Clinical Benefit of Immune Checkpoint Inhibitor Treatment—A Review From the Melanoma Perspective and Beyond

BACKGROUND: Immune checkpoint inhibition (ICI) with anti-CTLA-4 and/or anti-PD-1 antibodies is standard treatment for metastatic melanoma. Anti-PD-1 (pembrolizumab, nivolumab) and anti-PD-L1 antibodies (atezolizumab, durvalumab, and avelumab) have been approved for treatment of several other advance...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Buder-Bakhaya, Kristina, Hassel, Jessica C.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031714/
https://ncbi.nlm.nih.gov/pubmed/30002656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01474
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