Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells

How previous immunity influences immune memory recall and protection against related flaviviruses is largely unknown, yet encounter with multiple flaviviruses in a lifetime is increasingly likely. Using sequential challenges with dengue virus (DENV), yellow fever virus (YFV), and Japanese encephalit...

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Publicat a:Sci Adv
Autors principals: Saron, Wilfried A. A., Rathore, Abhay P. S., Ting, Lim, Ooi, Eng Eong, Low, Jenny, Abraham, Soman N., St. John, Ashley L.
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031378/
https://ncbi.nlm.nih.gov/pubmed/29978039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aar4297
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