EZH2-Mediated Epigenetic Suppression of GDF15 Predicts a Poor Prognosis and Regulates Cell Proliferation in Non-Small-Cell Lung Cancer

Growth differentiation factor 15 (GDF15), a member of the TGF-β superfamily of cytokines, has been reported to exert very heterogeneous functions in various tumors. However, its expression and roles in mediating non-small-cell lung cancer (NSCLC) progression remain unknown. In this study, we found t...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Lu, Xiyi, He, Xuezhi, Su, Jun, Wang, Jing, Liu, Xinyin, Xu, Kun, De, Wei, Zhang, Erbao, Guo, Renhua, Shi, Yuenian Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031151/
https://ncbi.nlm.nih.gov/pubmed/30195769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.05.016
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