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Cancer progression models and fitness landscapes: a many-to-many relationship
MOTIVATION: The identification of constraints, due to gene interactions, in the order of accumulation of mutations during cancer progression can allow us to single out therapeutic targets. Cancer progression models (CPMs) use genotype frequency data from cross-sectional samples to identify these con...
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| Pubblicato in: | Bioinformatics |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6031050/ https://ncbi.nlm.nih.gov/pubmed/29048486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx663 |
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