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HotSpot Wizard 3.0: web server for automated design of mutations and smart libraries based on sequence input information

HotSpot Wizard is a web server used for the automated identification of hotspots in semi-rational protein design to give improved protein stability, catalytic activity, substrate specificity and enantioselectivity. Since there are three orders of magnitude fewer protein structures than sequences in...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Sumbalova, Lenka, Stourac, Jan, Martinek, Tomas, Bednar, David, Damborsky, Jiri
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030891/
https://ncbi.nlm.nih.gov/pubmed/29796670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky417
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