Sources of nonlinearity in cDNA microarray expression measurements

BACKGROUND: A key assumption in the analysis of microarray data is that the quantified signal intensities are linearly related to the expression levels of the corresponding genes. To test this assumption, we experimentally examined the relationship between signal and expression for the two types of...

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Autors principals: Ramdas, Latha, Coombes, Kevin R, Baggerly, Keith, Abruzzo, Lynne, Highsmith, W Edward, Krogmann, Tammy, Hamilton, Stanley R, Zhang, Wei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC60308/
https://ncbi.nlm.nih.gov/pubmed/11737946
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