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The inhibitory effect of LPS on the expression of GPR81 lactate receptor in blood-brain barrier model in vitro

BACKGROUND: Lipopolysaccharide (LPS) is one of the main constituents of the cell wall of gram-negative bacteria. As an endotoxin, LPS induces neuroinflammation, which is associated with the blood-brain barrier impairment. Lactate is a metabolite with some significant physiological functions within t...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Boitsova, Elizaveta B., Morgun, Andrey V., Osipova, Elena D., Pozhilenkova, Elena A., Martinova, Galina P., Frolova, Olga V., Olovannikova, Raissa Ya, Tohidpour, Abolghasem, Gorina, Yana V., Panina, Yulia A., Salmina, Alla B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030740/
https://ncbi.nlm.nih.gov/pubmed/29973231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1233-2
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