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Importance of Metal-Ion Exchange for the Biological Activity of Coordination Complexes of the Biomimetic Ligand N4Py

[Image: see text] Metal coordination complexes can display interesting biological activity, as illustrated by the bleomycins (BLMs), a family of natural antibiotics that when coordinated to a redox-active metal ion, show antitumor activity. Yet, which metal ion is required for the activity in cells...

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Detalhes bibliográficos
Publicado no:Inorg Chem
Principais autores: Geersing, Arjan, Ségaud, Nathalie, van der Wijst, Monique G. P., Rots, Marianne G., Roelfes, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030684/
https://ncbi.nlm.nih.gov/pubmed/29916702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.8b00714
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