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Runx2 Suppression by miR-342 and miR-363 Inhibits Multiple Myeloma Progression

In multiple myeloma (MM), abnormal plasma cells accumulate and proliferate in the bone marrow. Recently, we observed that Runx2, a bone-specific transcription factor, is highly expressed in MM cells and is a major driver of MM progression in bone. The primary goal of the present study was to identif...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Res
Hauptverfasser: Gowda, Pramod S., Wildman, Benjamin J., Trotter, Timothy N., Xu, Xiaoxuan, Hao, Xiaoxiao, Hassan, Mohammad Q., Yang, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030427/
https://ncbi.nlm.nih.gov/pubmed/29592898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0606
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